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Use different injection sites for each compound - for example, tirzepatide in the abdomen and cagrilintide in the thigh or upper arm

Chika Anekwe, Obesity Medicine Clinical Director at Massachusetts General Hospital Weight Center and instructor at Harvard Medical School, points out that a common misconception is that everyone experiences major side effects

Potential Side Effects Common side effects of GLP-1 agonists, particularly during the initial weeks of weight loss treatment, include: Nausea Vomiting Diarrhea Headache Constipation Decreased appetite Pain in the right or middle upper stomach area Fatigue Dizziness Indigestion Injection site reactions (e.g., injection site rash, erythema) Conclusion GLP-1 agonists represent a promising pharmacological approach to weight management, offering significant benefits for individuals struggling with obesity or being overweight

Participants who only considered lifestyle changes lost about 2.4 percent of their body weight

But some people need it more than others

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