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Reported side effects include GI upset, headache, and rarely, anaphylaxis with IV administration

Abnormal histone modifications in PBMCs from patients with psoriasis vulgaris

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10.1038/nature01629 16 GladyshevV

For other confirmed or suspected malabsorption, vitamin B12 replacement should be offered and intramuscular treatment should be considered instead of oral treatment

This level of control is harder to achieve with oral supplements, where absorption can be influenced by factors like food intake and gastrointestinal health