For the last 20 years, they have been studying natural aging in older humans and aged mice in the Section of Endocrinology, Diabetes and Metabolism of the Department of Medicine
While there is no official "human dose" yet because it's still a research chemical, most lab studies use micro-doses to see these effects

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they act on growth hormone and incretin pathways respectively, and their use outside approved clinical trials is unsupported by robust clinical evidence
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The only variable introduced was the capsule