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Therefore, studies have investigated how CHAC1 is regulated in tumor cells and their microenvironment: Prostate cancer patients frequently develop resistance to docetaxel, a challenge in which cancer-associated fibroblasts (CAFs) have been shown to play a significant role through exosome-mediated signaling (Zhao et al

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& Kish, S

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Other important risk factors for hyperhomocysteinemia include obesity and cigarette smoking.1,3,7 Congenital defects in the enzymes that regulate homocysteine metabolism are a primary cause of hyperhomocysteinemia

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