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As a confirmation, subjects treated with androgen deprivation therapy showed an increased risk of DM and coronary artery diseases [75] , myocardial infarction [75,76] , CV mortality and sudden cardiac death [77,78] , and heart failure [79]

This confers an almost intrinsic resistance to traditional anti-cancer treatments, making immune checkpoint molecules attractive therapeutic targets

Even supplements can get in the way if overused

Several nutrients have clinical relevance in vitiligo management: Vitamin D commonly deficient in vitiligo patients

However, the more number of options, the higher the confusion

Another problem: Melanotan 2 is NOT FDA approved, and many products sold online may contain impurities or inaccurate dosing