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Semaglutide carries a specific warning about potential worsening of diabetic retinopathy in patients with pre-existing retinopathy, particularly with rapid improvement in glucose control

Thyroid Cancer: Tirzepatide may carry a theoretical risk for thyroid tumors, though this is based on animal studies and has not been confirmed in humans

It was a cohort study that examined 18,386 patients with overweight or obesity (mean baseline weight: 242lb) who received tirzepatide or semaglutide between May 2022 and September 2023

Effect of the glucagon-like peptide-1 receptor agonists semaglutide and liraglutide on kidney outcomes in patients with type 2 diabetes: pooled analysis of SUSTAIN 6 and LEADER

They treat diabetes in two different ways, but both have been proven highly effective

Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders