2019;6:Cd011265
Kahn SE, Hull RL, Utzschneider KM
Other possible GI symptoms include nausea, vomiting, abdominal discomfort, and diarrhea
Specific examples include: (1) pramlintide (amylin analog), which received FDA approval only after evidence standards shifted to accommodate an injectable adjunct therapy, having initially faced barriers related to delivery format and market positioning
We await the results of this trial, as they may provide valuable insights into the potential of relaxin-2 mimetics to improve outcomes for this patient population
In addition, the analysis of the EXSCEL trial revealed that a composite end-point of new macroalbuminuria, 40% eGFR decline or renal death was reduced by the addition of exenatide in T2DM [26]