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7.3 Treatment strategies Calcium channel blockers and opioid antagonists, such as naltrexone, have shown potential for managing heroin addiction and ischemic stroke (Peyravian et al., 2022)

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Regarding liver and kidney damage in MTX treatment, Bedoui stated that MTX hepatotoxicity may occur due to the depletion of folate reserves and MTX-polyglutamate formation in the liver (Reference Bedoui, Guillot and Slambarom41)

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Allergic reactions to any of the ingredients remain possible, though uncommon

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Volcano plots further highlighted the differential protein profiles induced by GLP1/E treatment

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Key takeaways A colonoscopy is the gold standard for detecting colorectal cancer, but its only as good as its preparation

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