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Change from baseline in body weight by week for all participants in the STEP-1 trial Weight regain and cardiometabolic effects after withdrawal of semaglutide

Safety concerns include pancreatitis, thyroid cancer, and severe gastrointestinal issues, and GLP-1 medications should be avoided in people with a history of these conditions [7]

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For mothers with type 2 diabetes, uncontrolled blood glucose also poses risks during the breastfeeding period, including increased susceptibility to infections and delayed healing

In addition, there was a lower incidence of nephropathy and a non-significantly higher incidence of retinopathy ( p = 0.33) in the liraglutide group in LEADER

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