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The reaction is catalyzed by a family of enzymes called Glutathione S-transferases (GSTs), which facilitate a nucleophilic attack, covalently binding the sulfur atom of glutathione directly to the toxic Phase I metabolite

Aim for at least 20-25g of high-quality protein per meal

This is intended to protect the molecule from premature oxidation or breakdown

This is currently lacking, with existing recommendations largely anecdotal or extrapolated from animal data

The combination addresses both insulin resistance (metformin) and appetite signaling dysfunction (GLP-1), creating complementary metabolic benefits for patients with obesity and type 2 diabetes

Supplementing both may support fat metabolism and overall energy levels during exercise