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3 January 2020
What the Evidence Can and Cannot Show Yet The current evidence suggests a possible signal, not a settled treatment standard
Cell Death Differ 23 , 369379 (2016)
The average 4 to 6 pound reduction over 26 to 78 weeks is statistically significant but smaller than what most patients expect from "semaglutide." For context, the STEP 1 trial of injectable semaglutide 2.4 mg weekly showed average weight loss of 33 pounds over 68 weeks in patients without diabetes
Still, Second Nature recommend staying on the lowest effective dose for as long as possible
Contraindication There are medical situations where it is not recommended to use Femara, highlighting the importance of personalized medicine
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