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Neurosci Lett 156 : 153157

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Data from clinical studies In an observational study involving 20 diabetic subjects receiving background metformin therapy, exenatide treatment over 16 weeks resulted in improved flow-mediated vasodilation of the brachial artery following 5 min of forearm ischemia, as assessed by ultrasound echocardiography, compared to patients treated with glimepiride [85]

Testosterone replacement may benefit men with documented hypogonadism (typically defined as morning total testosterone 4 hours) Penile injury or trauma Sudden onset of severe penile pain or curvature Erectile dysfunction can serve as an early warning sign of cardiovascular disease, often preceding heart attacks or strokes by several years