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Indeed in healthy humans vagal stimulation, achieved by modified sham feeding technique (in which nutrients are chewed and tasted but not swallowed) has an inhibitory effect on ghrelin release comparable to real feeding (Arosio et al., 2004)

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(1995): Effects of acetyl-L-carnitine treatment and stress exposure on the nerve growth factor receptor (p75NGFR) mRNA level in the central nervous system of aged rats

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Research indicates Epithalon's chronobiotic activity extends beyond simple hormone stimulation to include structural preservation of pineal tissue