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While 1 or 2 in a million people getting a side effect would show up, it would not show up in the original studies for FDA approval, which were conducted on a much smaller number of patients, said Reddy

Some ignore temperature rise

Novo Nordisk has faced challenges recently

"GLP-1 agonists can delay gastric emptying and cause gastroparesis (paralysis of the stomach), leading to food remaining in the stomach and increasing anesthesia-related risks," said Christopher T

Virta member Becky remembers feeling so drained that exercise felt impossible

These are usually transient and can be managed by drinking plenty of water and starting with a smaller dose