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While neither peptide requires FDA prescription approval, medical supervision is strongly recommended for optimal results and safety monitoring

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Long-term use appears well-tolerated when dosing is appropriate and monitored

Symptoms may include muscle weakness, diarrhoea, vision problems, etc

This suggests that the centrosomal and spindle defects caused by CDK5RAP2 depletion or CDK5RAP2(51-100) expression did not activate the spindle assembly checkpoint