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According to the Wegovy Summary of Product Characteristics (SmPC), treatment should be discontinued if a patient has not lost at least 5% of their initial body weight after 12 weeks on the maintenance dose (2.4 mg once weekly)
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PMID: 1704369
First, we treated the diabetic mice and the aged mice with GLP-1R agonist liraglutide and detected the sperm parameters
These findings were further supported by studies with albiglutide, where the potency of the GLP-1RA binding covalently to albumin necessitated a high dose to obtain clinically relevant efficacy (54)
Robert F
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