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Gillette H

In normal conditions, the loading conditions activate the Piezo1 channel in bone marrow mesenchymal stem cells, which leads to the repression of the Ccl2-Lcn2 inflammatory cascade and a tendency toward osteogenesis instead of adipogenesis (290)

E.GatchM

Regarding plasma B12 - this is not the case, serum B12 often remains highly elevated (well over the normal range) even while symptoms return - this is why testing B12 once treatment begins is not recommended

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