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There are few GLP-1 agonists available around the world

These headaches can vary from mild to intense and may be temporary or persist throughout the treatment period

Weight-loss drugs may not be suitable for all and can be associated with side effects such as constipation (difficulty passing stools), nausea, vomiting, headache, fatigue, diarrhea, mood changes, palpitations (irregular heartbeat), etc

The FDA has approved these medications for use in patients with type 2 diabetes and for weight loss in individuals meeting certain criteria, such as BMI and weight-related conditions

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The following symptoms warrant prompt medical attention and patients should contact their GP or seek urgent care if they experience: Severe or persistent abdominal pain , which may indicate pancreatitis a recognised risk with GLP-1-containing therapies [13] Jaundice, right upper quadrant pain, or fever , which may suggest gallbladder disease Signs of dehydration or reduced kidney function , such as dizziness, markedly reduced urine output, or confusion, particularly if vomiting or diarrhoea is prolonged Visual changes , particularly in individuals with pre-existing diabetic retinopathy Patients taking retatrutide alongside insulin or a sulfonylurea should be aware of an increased risk of hypoglycaemia (low blood sugar)