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The shorter TB 500 peptide retains the bioactive segment that promotes new blood vessel formation and modulates inflammatory cytokines

doi: 10.3389/fpsyt.2026.1766770 Received 13 December 2025 Revised 13 February 2026 Accepted 18 February 2026 Published 10 March 2026 Volume 17 - 2026 Edited by Yi-lang Tang, United States Department of Veterans Affairs, United States Reviewed by Ming-Fen Ho, Mayo Clinic, United States Aristea Psilopanagioti, University of Patras, Greece Updates Copyright 2026 Abegaz, Ahmed, Bhagavathula and Frietze

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This age-associated carnitine depletion contributes to mitochondrial dysfunction, reduced physical capacity, and metabolic inflexibility