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Given that NRF2 regulates the expression of numerous genes associated with oxidative stress and inflammation, the application of omics methodologies, which allow for the simultaneous measurement of hundreds to thousands of molecular targets, may help to fully delineate how NRF2 activity influences the complex interplay between redox homeostasis and sleep regulation

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Recently, the BBB opening procedure was further reported to clear the deposited A plaque due to microglia activation

Glutathione also has a role in protein synthesis, prostaglandin and leukotriene synthesis, amino acid transport and iron metabolism