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10.1074/jbc.M111.323287 J
The kinetic data were analyzed by using the GraphPad Prism software with a simple pseudo first-order reaction model to estimate the apparent kinetic parameters
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The authors compare multiple senolytic strategies including FOXO4-DRI, dasatinib plus quercetin, navitoclax, and fisetin, evaluating mechanisms of action, selectivity profiles, and safety considerations for each approach
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