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[263] In 2016, Hanks endorsed former Secretary of State Hillary Clinton in the 2016 presidential election

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Important safety information: GLP-1 medications carry an FDA boxed warning about thyroid C-cell tumors seen in animal studies and are contraindicated with a personal or family history of medullary thyroid carcinoma (MTC) or MEN2

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So although you may have met your goal, taking GLP-1s long-term helps you with weight management

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Results suggest orforglipron leads to significant weight loss, at an average of 7.5% of body weight over 72 weeks for those on a 6mg dose, which increased to 8.4% with 12mg and 11.2% with 36mg, compared with 2.1% with placebo

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As endoscopic evaluation was recommended but not mandatory, there was a tendency of patients without specific complications to refuse further endoscopic evaluation

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