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Pharm Biol (2022) 60(1):155665

In hypertension, GAS5 is significantly downregulated in endothelial cells (ECs) and VSMCs, and its silencing exacerbates vascular remodeling, increases capillary leakage, and promotes endothelial dysfunction by modulating -catenin signaling

However, the translational gap between basic research and clinical application remains unresolved

[29] Separately, Zepbound may also be covered through Part D when it's prescribed for obstructive sleep apnea (OSA) or, as Mounjaro, for type 2 diabetes

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