According to studies , severe nausea and headaches were common while taking Melanotan, and some participants experienced uncontrolled darkening of existing moles and pigmentation
Novinscak et al., 2008
The authors reported that in obese mice, daily AOD-9604 administration over 14 days produced significant reductions in body weight gain, decreases in adipose tissue mass, and increases in fat oxidation, with effect sizes comparable to those of full-length human growth hormone [1]
In addition to weight loss, some studies propose that AOD-9604 may aid in cartilage repair, joint recovery, and anti-inflammatory effects, making it a potential therapeutic option beyond fat reduction
Protein-bound molecules, including drugs, are eliminated by proximal tubular secretion via a well-coordinated process of uptake by the tubular cells at the blood-facing basolateral site and secretion into the tubular lumen
PLoS One 8:e54794