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Participants receiving the highest dose of orforglipron achieved a mean weight reduction of approximately 12.4% from baseline, equating to an average loss of 27.3 lb compared with 2.2 lb in the placebo group
The two main hormones are estrogen, which is known to increase cholesterol, and progesterone, which slows down gallbladder contractions
All participants gave written informed consent before enrollment into the study
Continuing Education in Anaesthesia Critical Care & Pain Oxford University Press, vol
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