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infection dampens NLRP3 activation by modulating mitochondrial ROS production, partly through upregulation of antioxidant enzymes such as superoxide dismutases (SOD1 and SOD2), catalase (CAT), and glutathione peroxidase (GPx)

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Low molecular mass disulfides can be excluded, because serum depleted of high mass components by filtration does not show any reactivity with CDNB (Figure 2b)

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