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Human clinical trials for the specific GLP3 + cagrilintide combination are absent from peer-reviewed literature

As in the LEAN study, the primary outcome is histologic resolution of NASH without worsening of fibrosis after 72 weeks of treatment, while secondary outcomes include improvement in liver fibrosis (1 stage) with no worsening of NASH, NAFLD activity score, as well as multiple serum markers of fibrosis

Most patients see meaningful regrowth after completing 3 cycles, approximately 3 months

Khan said that, aside from diabetes and weight loss, studies have shown GLP-1s reduce major adverse cardiovascular events, help prevent the onset of diabetes and also improve sleep apnea, arthritis and fatty liver disease outcomes

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This technique can be used for surgery and postoperative pain management in patients undergoing a wide variety of knee, lower leg, foot, and ankle surgeries