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Maintenance Dosing: Once the desired therapeutic effect is achieved, a maintenance dose is established

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These drugs are labeled as class 1 ferroptosis inducers, and those targeting GPX4 activity are considered class 2 ferroptosis inducers

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Vitamin C is a powerful antioxidant, and Glutathione recycles it, allowing both to work more effectively

Then, DCFH is oxidized to DCF by intracellular H 2 O 2 , generating the fluorophore DCF ( excitation = 488 nm, emission = 530 nm)