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Nanomedicine platforms offer precise tools for macrophage modulation, enabling the targeted delivery of polarization-inducing agents directly to the TME while sparing peripheral tissues ( A multifunctional poly(amino acid) nanomedicine (PM-DPA/R848) has been developed that encapsulates the TLR7/8 agonist resiquimod (R848) within a nanocarrier composed of poly(L-methionine) and alendronate-functionalized DSPE-PEG ( Calcium carbonate (CaCO3)-based nanosystems have been engineered to simultaneously neutralize the acidic TME and reprogram TAM polarization
We do not know whether the treatment affects metabolism long-term
The New England journal of medicine, 393(1), 2636
The CDC is currently investigating an outbreak of illness caused by Salmonella infection associated with the use of kratom
Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC), 2326 October 2023: GLP-1 receptor agonists available evidence not supporting link with thyroid cancer
For year-round use, these rare events reinforce the importance of proper hydration, regular health monitoring, and communication with a healthcare professional if anything feels off
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