Though the regulatory agency generally does accept the determinations of panels like these, it can and has rejected panel votes in the past
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Most protocols recommend picking one general area for consistency, then rotating specific spots within that area
Do not use on broken or infected skin unless advised by a healthcare professional
Fischer TW, Zmijewski MA, Zbytek B, Sweatman TW, Slominski RM, Wortsman J, Slominski A (2006) Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines
It also has anti-inflammatory benefits