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Gastrointestinal effects: Mounjaro commonly causes gastrointestinal side effects, including nausea, vomiting, diarrhoea, and reduced appetite, particularly when starting treatment or increasing the dose

51 Park et al 52 found that empagliflozin, dulaglutide and a combination of both significantly attenuated the increase in cells, especially macrophages and neutrophils, in airway alveolar lavage fluid induced by a high-fat diet in mice, reduced the expression of IL-17 and transforming growth factor (TGF)-1, and decreased the differentiation of Th cells to Th1 and Th17, thereby achieving a reduced inflammatory response

doi: 10.1016/j.bpj.2010.07.063 96

In their lyophilised (freeze-dried) form, many peptides can remain stable at room temperature for short periods, although cooler conditions are always preferred

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