The basic principle causing the radiation-induced toxicity is the excessive generation of reactive oxygen species (ROS) due to the radiolysis of cellular water, which in turn oxidizes the critical biomolecules such as lipid, protein, and DNA [36,37,38,39]
Male mice were used for studies unless indicated
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These complications are uncommon and are more related to rapid weight loss, rather than the treatments themselves, but require immediate medical attention if symptoms persist
As a limitation, the current study examined only the thalamus, precluding direct conclusions about regional specificity
Additionally, glutathione can help to play a role in the detoxification of synthetic substances (xenobiotics) and substances that originate within your body (endogenous compounds)