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Concurrently, its localization in the mucus layer raises inquiries regarding long-term effects on mucosal integrity in various host contexts (44)

These findings tightly link ROS and Nrf2 to ER oxidative protein folding and calcium signaling, establishing a regulatory mechanism for protein oxidative folding-Nrf2-ER calcium axis (Figure 7)

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GSH (-L-glutamyl-L-cysteinylglycine) is an endogenous tripeptide found mainly in liver tissues, which are the main tissues involved in its biosynthesis

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