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Therapeutic applications focus on insomnia and difficulty falling or staying asleep, insufficient deep sleep despite adequate sleep duration, sleep disruption from stress or irregular schedules, recovery optimization for athletes or high performers, circadian rhythm disorders from travel or shift work, sleep quality decline associated with aging, and comprehensive wellness protocols recognizing sleep as foundational to metabolic health, cognitive function, immune resilience, and longevity

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doi: 10.1136/jnnp.2009.194399 25 BoeynaemsS.BogaertE.KovacsD.KonijnenbergA.TimmermanE.VolkovA.et al

On the other hand, proteins or peptides generally possess a definite amino acids sequence, fixed molecular weight, uniform physicochemical properties, and show less batch to batch variation