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doi: 10.3389/fphar.2025.1543870 Received 12 December 2024 Accepted 25 March 2025 Published 14 May 2025 Volume 16 - 2025 Edited by Sabrina Petralla, Heidelberg University, Germany Reviewed by Yuan Wei, Jiangsu University, China Shameer Pillarisetti, University of Studies G

Severe vitamin B12 deficiency can lead to memory loss, joint pain, and vision problems, among other complications

Simultaneously, insulin resistance, up- and downregulation of vessel GLUT and increased BBB permeability drive systemic hyperglycemia and reduced utilization of glucose at the cellular level [38, 58, 61]

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In addition, experimental studies have shown that the effective oral dose in rats is 10 g/kg, which is estimated to be equivalent to 1.6 g/kg, or: 110 g for a 150lb person 145 g for a 200lb person 180 g for a 250lb person Benefits of BPC 157 supplement The benefits of BPC 157 as a supplement or peptide therapy are shown in the following ways: Promotes wound healing Accelerates tissue regeneration Reduces inflammation Increases blood flow Relieves joint pain Enhances immune function Reduces muscle weakness, debility and muscle damage Reduces nerve damage and cerebral oedema Side Effects No significant serious adverse reactions have been reported with BPC 157