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New England Journal of Medicine, 2007;357:2359-2370

Nevertheless, poor graft survival, heterogeneity among cell populations, risks of tumorigenicity, and variability in delivery methods continue to hinder clinical translation

2014), affecting both the balance of hepatic free fatty acids and the expression of key lipid metabolism genes in the liver (Suciu et al

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They started with a natural hormone called amylin and made specific changes to its structure to make it more effective and last longer in the body

This occurs because of increased synthesis of type I collagen by hepatic stellate cells (HSCs) and increased production of the extracellular matrix protein called osteopontin