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Median t max was longer for the fasting (1.75 h) versus reference groups (1.00 h), while no obvious difference was seen for t 1/2 (160 h and 152 h, respectively) between the fasting and reference groups

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If using a PPI, the morning dose provides all-day coverage, but adding an evening H2 blocker specifically for nighttime protection is a well-established combination strategy

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Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors currently undergoing clinical trials