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Deletion of PLC-3 or PLC-4 genes showed no phenotypic effects in mice, but sperms from PLC-4-deficient mice showed a defective acrosomal reaction, a process required for fertilization (Fukami et al., 2001

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Co-culture systems involving neurons, microglia, and astrocytes could elucidate the complex interactions within the neuroimmune network and provide deeper insights into the multifaceted roles of Irisin

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Tirzepatide has shown the largest results so far, with average reductions ranging from 15% to nearly 21% over 72 weeks, depending on dose