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SPI-1005 is an oral small molecule that acts as a true catalytic mimic of GPx1
Acknowledgements We thank D
Cell lysates and basilar supernatants were run in 4%12% sodium dodecyl sulphatepolyacrylamide (SDS-PAGE) gels (Invitrogen) and transferred onto polyvinylidene difluoride membrane (Invitrogen)
It also comes in a pineapple and grapefruit flavour, although we didn't try these
Thiol proteins, redox modulation and parenchymal lung disease
Synthesis of Amodiaquine Quinoneimine (AQ-QI) and Desethylamodiaquine Quinoneimine (DEAQ-QI) Synthesis of AQ-QI and DEAQ-QI was adapted from a method published previously, with a few modifications ( in vacuo and then applied to a silica-60 column to remove the tracing AQ or DEAQ
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