Across seven randomized controlled trials involving approximately 680 adult participants, mazdutide demonstrated a mean weight loss of 6.22%, with non-diabetic individuals achieving reductions of up to 8.44% in body weight
"There was no concern there were any Wada rules being broken
Gastrointestinal Side Effects GLP-1 receptor agonists commonly cause GI side effects nausea, bloating, reflux/heartburn, constipation, and sometimes vomiting
Fibre-rich foods like vegetables, whole grains, and pulses
GI side effects may emerge but tend to be manageable because of the gradual titration
This is especially important when working with GLP-1 drugs, where the patients status needs to be accurately captured