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Modified versions of GLP-1 have been developed to be more potent and have longer-lasting effects, and they are currently used in clinical practice to treat type-2 diabetes

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This variation underscored the importance of exploring a range of dosages rather than assuming a single best number

Superseded by weekly options and discontinued in the US

Numerous gut- and brain-derived peptides exert potent anorectic or orexigenic effects, often with effect sizes comparable to or exceeding those of GLP-1 in preclinical models