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Curr Opin Endocrinol Diabetes Obes (2012) 19(1):4752

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Its convenient to take but the effects take time because you need to digest the content first

Under conditions of reduced portal insulin-to-glucagon ratio, lipolysis increases in adipose tissue and releases non-esterifed fatty acids which are converted to ketone bodies in the liver through mitochondrial beta oxidation and ketogenesis [25], resulting in a metabolic condition resembling a prolonged fast [26]

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However, like semaglutide, retatrutide's effect on stomach emptying lessens over time, which might need a break from the drug to restore its effectiveness