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Structure Patients treated with tesamorelin for 52 weeks (T-T group) showed no change between Weeks 26 and 52 in mean trunk fat (increase of 0.1 kg in Study 1 and decrease of 0.5 kg in Study 2, respectively, compared with an increase of 1.4 kg in patients in the T-P group in Study 1 and an increase of 1.09 kg in Study 2, respectively) nor was there a change from Week 26 baseline in mean lean body mass (decrease of 0.1 kg in Study 1 and increase of 0.1 kg in Study 2, respectively, compared with a decrease of 1.8 kg in patients in the T-P group in Study 1 and a decrease of 1.7 kg in Study 2, respectively)
Hathaway, D
The side effect profile is more serious than GLP1R agonists , including depression and suicidal ideation and it is not approved for other types of obesity
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However, Ipamorelin is not approved by the FDA for any specific medical condition and is often used under research or experimental settings
Lancet 390 (10113), 26272642 (2017)
