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Note that the norleucine substitution at position 4 has already removed the methionine thioether present in native alpha-MSH, so tryptophan governs handling

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Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor