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Telomeres, the protective caps at the end of DNA strands, shorten over time, leading to cellular ageing and eventual cell death
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9Kathleen, M Dungan, et alOnce-weeklydulaglutide versus once-daily liraglutide in metformin-treated patients withtype 2 diabetes( AWARD-6) : a randomisedopen-labelphase3 non-inferiority trial JLancet2014384 ( 9951) : 1349 1357, 10Naver S, Jimenez-Solem E, Christensen M, et al.Dulaglutide: a novel once-weekly glucagon-like peptide-1 receptor agonist[J].Clinical Investigation, 2014, 4(8): 729-743
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Cells were gated for singlets, and the GeoMean NAO, TMRE or MitoSOX Red fluorescence was evaluated using FlowJo software