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GLP-1s also reduce your appetite, so you end up eating less
PubMed laboratory research record [PMID: 2770943] PubMed record related to this compound for laboratory literature review
Gut dysbiosis (an imbalance in the microbiome) has also been shown to lead to GLP-1 resistance, meaning your body doesnt properly respond to GLP-1 even when its released
The problem is that translation from rodent models to human outcomes is notoriously unreliable, and we've been burned by promising animal data that didn't pan out in humans more times than anyone wants to count
Furthermore, diabetic rats treated with DPP4 inhibitors showed lower HbA1c levels compared to diabetic control animals
When I sat down with Dr
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