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Now it seems oral small-molecule GLP-1s also dial back eating for pleasure by engaging a brain reward circuit. Given the effect of these drugs on eating for pleasure, future studies could explore whether small-molecule GLP-1s can also suppress cravings for other addictive substances

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Studies use the combination to characterise the kinetics of dual-receptor desensitisation examining GHRH-R versus GHS-R1a desensitisation time courses, the differential contributions of each receptor to the declining GH response with repeated stimulation, and the recovery kinetics of somatotroph responsiveness following stimulation washout

Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress

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