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86,87 Differing from the effects observed in T2DM, the therapeutic efficacy of dulaglutide for MASLD is not particularly compelling based on current statistics

This produces a senescent phenotype of skin cells, leads to the release of innate immune molecules, which trigger autoimmunity, and ultimately causes dysfunction and death of melanocytes

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it also causes systemic inflammation that breaks down cartilage and bone, leaving people doubting their ability to live their daily lives