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Our findings demonstrated that metformin alleviated OA progression against oxidative stress through the activation of Nrf2 signaling pathway, which suggest the potential therapeutic option of metformin for osteoarthritis

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10.1096/fj.12-226225 92

The purified GR was incubated at the same temperature for 60 min before the activity measurement at each temperature

Protocol Notes One weekly retatrutide shot + 1-2 daily CJC/Ipa shots