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doi: 10.1016/j.phymed.2025.156901 158 PeiFDuanJTanLGuCMiaoJLiuSet al
MizoguchiHYamadaKNiwaMMouriAMizunoTNodaYet alReduction of methamphetamine-induced sensitization and reward in matrix metalloproteinase-2 and -9-deficient mice
Specifically, in the leaky gut state, gut microbiota dysbiosis occurs, the expression of intestinal epithelial junction proteins (e.g., tight junction proteins) decreases, and intestinal permeability increases, forming a leaky gut (165)
The evidence base, such as it is, differs meaningfully across clinical targets, and it is worth examining each major application area on its own terms
Bibcode:2007PhyRv..87.1215B